In a 12 week clinical study,

AUSTEDO (deutetrabenazine) tablets significantly reduced Huntington's disease (HD) chorea1

People taking AUSTEDO saw >2x reduction in HD chorea movements vs placebo*

*4.4-point improvement in people taking AUSTEDO vs 1.9 in people taking placebo based on Total Maximal Chorea (TMC) score. The TMC score is used to measure HD chorea movements in the face, mouth, trunk, both arms, and both legs.

People taking AUSTEDO saw more then 2 times reduction in HD chorea movements vs placebo.

*4.4-point improvement in people taking AUSTEDO vs 1.9 in people taking placebo based on Total Maximal Chorea (TMC) score. The TMC score is used to measure HD chorea movements in the face, mouth, trunk, both arms, and both legs.

An open label study showed

symptom relief was sustained for

~3 YEARS2‡

An open label study is a drug trial in which all participants are aware of the drug being tested.
Mean TMC score changed minimally from Week 8 to Week 132 (or end of treatment).

People on AUSTEDO reported improvement in their ability to perform daily activities like3,4:

    • Climbing stairs
    • Moderate to vigorous activities
    • Lifting/carrying groceries
    • Bathing
    • Walking
    • Dressing
    • Bending, kneeling, or stooping

People taking AUSTEDO achieved greater improvement in the SF-36§ Physical Functioning Score at 12 weeks vs placebo4

§SF-36=Short form 36 item survey assessing health-related quality of life.

Both patients and doctors rated overall HD symptoms as "much improved" or "very much improved" at 12 weeks with AUSTEDO.1,4

51% of people on AUSTEDO saw treatment success vs 20% on placebo

Very much improved/Much improved

51%
of people on AUSTEDO saw treatment success

vs placebo

20%

42% of doctors saw treatment success vs 13% on placebo

Very much improved/Much improved

42%
of doctors saw treatment success

vs placebo

13%

Treatment success is measured by perceived improvement in TMC score.

AUSTEDO does not cure the cause of the involuntary movements and it does not treat the other symptoms of HD, such as problems with thinking or emotions.

Now is the time to talk to your doctor about how AUSTEDO may help reduce your HD chorea movements.1

DownloadGet the discussion guide

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