Your prescribed dose may require a combination of AUSTEDO® tablet strengths:

Your doctor may increase your dose of AUSTEDO® each week for several weeks to find the dose that is appropriate for you. This process is known as titration. It’s important to follow your doctor’s instructions during this process. While some people may start to experience treatment benefits sooner, it may take up to 12 weeks to reach the full benefits of AUSTEDO®.

AUSTEDO® (deutetrabenazine) tablets are Available in 3 Strengths: 6 mg, 9 mg, and 12 mg AUSTEDO® (deutetrabenazine) tablets are Available in 3 Strengths: 6 mg, 9 mg, and 12 mg AUSTEDO® (deutetrabenazine) tablets are Available in 3 Strengths: 6 mg, 9 mg, and 12 mg AUSTEDO® (deutetrabenazine) tablets are Available in 3 Strengths: 6 mg, 9 mg, and 12 mg

tablets not actual size

tablets not actual size


Take AUSTEDO® exactly as prescribed Take AUSTEDO® exactly as prescribed

Exactly as prescribed

Take AUSTEDO® exactly as prescribed Take AUSTEDO® exactly as prescribed

By mouth

Take AUSTEDO® exactly as prescribed Take AUSTEDO® exactly as prescribed


Take AUSTEDO® exactly as prescribed Take AUSTEDO® exactly as prescribed

With food

Do not chew, crush, or break tablets before swallowing. If you cannot swallow AUSTEDO® tablets whole, tell your healthcare provider. You may need a different medicine.

Treatment tips

Treating your condition can be complicated. Sometimes it’s difficult to follow all of your doctor’s instructions. Use these tips to help ensure you take AUSTEDO® as prescribed:

Set a routine

  • Create and follow a dosing routine. Remember that AUSTEDO® must be taken exactly as prescribed.
  • Set an alarm as a treatment reminder.
  • Keep your AUSTEDO® tablets in the same place so you know where they are.

Record your treatment

  • Use the Shared Solutions® Daily Treatment and Activity Log to record when AUSTEDO® is taken and note any questions or concerns you may have for your doctor.

Have a plan

  • Before starting AUSTEDO®, you should talk to your doctor about what to do if you miss a dose.
  • Add your dosing schedule to your other daily routines so you will be less likely to miss a dose.
  • Tell your doctor if you stop taking AUSTEDO® for more than 1 week. Do not take another dose until you talk to your doctor.

For additional information about how to take AUSTEDO®, please read the Medication Guide.
Ask your doctor if you have any questions about taking AUSTEDO®.

Switching from tetrabenazine1,2

When switching to AUSTEDO® from tetrabenazine, you can start AUSTEDO® the day after you stop tetrabenazine. This means you can continue treating your HD chorea without missing a dose.

In a clinical study, 37 people with HD chorea switched overnight from tetrabenazine to AUSTEDO®. People in the study received AUSTEDO® at approximately half the dose of tetrabenazine.

Switching from tetrabenazine to AUSTEDO®

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Approved Uses

AUSTEDO® is a prescription medicine that is used to treat:

  • the involuntary movements (chorea) of Huntington’s disease. AUSTEDO® does not cure the cause of the involuntary movements, and it does not treat other symptoms of Huntington’s disease, such as problems with thinking or emotions.
  • movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).

It is not known if AUSTEDO® is safe and effective in children.

Important Safety Information

AUSTEDO® can cause serious side effects in people with Huntington’s disease, including: depression, suicidal thoughts, or suicidal actions.
Do not start taking AUSTEDO® if you are depressed (have untreated depression or depression that is not well controlled by medicine) or have suicidal thoughts. Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts or feelings. This is especially important when AUSTEDO® is started and when the dose is changed. Call your healthcare provider right away if you become depressed, have unusual changes in mood or behavior, or have thoughts of suicide.

Do not take AUSTEDO® if you:

  • have Huntington’s disease and are depressed or have thoughts of suicide.
  • have liver problems.
  • are taking a monoamine oxidase inhibitor (MAOI) medicine. Do not take an MAOI within 14 days after you stop taking AUSTEDO®. Do not start AUSTEDO® if you stopped taking an MAOI in the last 14 days. Ask your healthcare provider or pharmacist if you are not sure.
  • are taking reserpine. Do not take medicines that contain reserpine (such as Serpalan® and Renese®-R) with AUSTEDO®. If your healthcare provider plans to switch you from taking reserpine to AUSTEDO®, you must wait at least 20 days after your last dose of reserpine before you start taking AUSTEDO®.
  • are taking tetrabenazine (Xenazine®). If your healthcare provider plans to switch you from tetrabenazine (Xenazine®) to AUSTEDO®, take your first dose of AUSTEDO® on the day after your last dose of tetrabenazine (Xenazine®).
  • are taking valbenazine (Ingrezza®).

Other possible serious side effects include:

  • Irregular heartbeat (QT prolongation). AUSTEDO® increases your chance of having certain changes in the electrical activity in your heart. These changes can lead to a dangerous abnormal heartbeat. Taking AUSTEDO® with certain medicines may increase this chance. If you are at risk of QT prolongation, your healthcare provider should check your heart before and after increasing your AUSTEDO® dose above 24 mg a day.
  • Neuroleptic Malignant Syndrome. Call your healthcare provider right away and go to the nearest emergency room if you develop these signs and symptoms that do not have another obvious cause: high fever, stiff muscles, problems thinking, very fast or uneven heartbeat, or increased sweating.
  • Restlessness. You may get a condition where you feel a strong urge to move. This is called akathisia.
  • Parkinsonism. Symptoms include: slight shaking, body stiffness, trouble moving, trouble keeping your balance, or falls.

Sleepiness (sedation) is a common side effect of AUSTEDO®. While taking AUSTEDO®, do not drive a car or operate dangerous machinery until you know how AUSTEDO® affects you. Drinking alcohol and taking other drugs that may also cause sleepiness while you are taking AUSTEDO® may increase any sleepiness caused by AUSTEDO®.

The most common side effects of AUSTEDO® in people with Huntington’s disease include sleepiness (sedation), diarrhea, tiredness, and dry mouth.

The most common side effects of AUSTEDO® in people with tardive dyskinesia include inflammation of the nose and throat (nasopharyngitis) and problems sleeping (insomnia).

These are not all the possible side effects of AUSTEDO®. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Please read the accompanying Medication Guide.

References: 1. AUSTEDO® (deutetrabenazine) tablets current Prescribing Information. Teva Pharmaceuticals USA, Inc. 2. Frank S, Stamler D, Kayson E, et al. Safety of converting from tetrabenazine to deutetrabenazine for the treatment of chorea. JAMA Neurol. 2017;74(8):977–982.