Huntington’s disease (HD) is a neurological, hereditary disorder that affects nerve cells in the brain. HD causes physical, emotional, behavioral, and cognitive issues, and has symptoms that can be disruptive to relationships, jobs, and everyday activities. Some symptoms can make performing daily tasks challenging and may eventually prevent some tasks altogether, such as driving or managing a job or a household.1,2

AUSTEDO® (deutetrabenazine) tablets is a medicine to treat HD chorea. It does not treat other symptoms of HD, such as problems with thinking or emotions.

Chorea is the most visible symptom of HD. It may appear as unexpected and uncontrolled jerking and twisting body movements. These movements can be large or small, and may worsen with stress.

Signs of chorea may include1,3,4:

Flicking the fingers Flicking the fingers

Flicking the fingers

Flailing of the arms or legs Flailing of the arms or legs

Flailing of the arms or legs

Shrugging the shoulders Shrugging the shoulders

Shrugging the shoulders

Having a grimacing look Having a grimacing look

Having a grimacing look

Irregular eye movements or blinking Irregular eye movements or blinking

Irregular eye movements or blinking

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References: 1. Nance M, Paulsen JS, Rosenblatt A, Wheelock V. A physician’s guide to the management of Huntington’s disease. 3rd ed. Huntington’s Disease Society of America website. http://hdsa.org/wp-content/uploads/2015/03/PhysiciansGuide_3rd-Edition.pdf. Published 2011. Accessed September 23, 2019. 2. Huntington’s Disease: A Family Guide. Huntington’s Disease Society of America website. http://hdsa.org/wp-content/uploads/2015/03/HDSA_FamilyGuide.pdf. Published 2016. Accessed September 23, 2019. 3. Fekete R, Jankovic J. Upper facial chorea in Huntington disease. J Clin Mov Disord. 2014;1(7). doi:10.1186/2054-7072-1-7. 4. A caregiver’s guide to Huntington’s Disease. Huntington’s Disease Society of America website. http://hdsa.org/wp-content/uploads/2015/03/A-Caregivers-Guide-to-HD.pdf. Published March 2011. Accessed September 23, 2019.