Huntington’s disease (HD) is a neurological, hereditary disorder that affects nerve cells in the brain. HD causes physical, emotional, behavioral, and cognitive issues, and has symptoms that can be disruptive to relationships, jobs, and everyday activities. Some symptoms can make performing daily tasks challenging and may eventually prevent some tasks altogether, such as driving or managing a job or a household.1,2

There are 3 main categories of Huntington’s disease symptoms2:

Memory

(cognition/
thinking)

Mood

(emotion/
behavior)

Movement

(motor symptoms,
including chorea)

What is HD chorea?

Chorea is the most visible symptom of HD. It may appear as unexpected and uncontrolled jerking and twisting body movements. These movements can be anything from mild to severe and may worsen with stress.1-3

For people with Huntington’s disease, an abnormal increase in the release of dopamine can cause chorea.

Dopamine, a chemical in the brain that is responsible for many body functions, needs to maintain a specific balance to keep those functions working normally. One of these is motor function, or movement.4,5

AUSTEDO (deutetrabenazine) tablets is a medicine to treat HD chorea. It does not treat other symptoms of HD, such as problems with thinking or emotions.4

Signs of chorea may include1-3:

Flicking the fingers

Flailing of the arms or legs

Shrugging the shoulders

Having a grimacing look

Twisting or jerking

Irregular eye movements or blinking

Experiencing HD chorea symptoms? Start a discussion with your doctor.

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