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for Tardive Dyskinesia in Adults

What is the impact of
tardive dyskinesia (TD)?

Explore below to learn more about TD, its causes and symptoms, and its impact.

Once-daily AUSTEDO XR contains the same active ingredient as twice-daily AUSTEDO® (deutetrabenazine) tablets. Data on this page is based on twice-daily dosing.1

What does TD look like,
and what causes TD?1-9

TD can:

  • Cause repetitive and involuntary movements
  • Appear in the face, arms, legs, and trunk
  • Look like twitching, shaking, or jerking

Certain prescription medications used to treat mental health or gastrointestinal conditions can cause TD. It’s more than a side effect of these medications—it’s a real condition with its own diagnosis and treatment plan. It’s important to continue treating your mental health condition and also treat TD.


Take the next step with AUSTEDO XR

Recognizing TD symptoms

Healthcare providers don’t always see or ask about involuntary movements, which is why it’s important to share what
you’re experiencing during your appointment. Watch these videos to see what symptoms can look like.

Man experiencing ankle twisting and rolling symptom of TD. Woman experiencing arm and hand twitching symptom of TD. Woman experiencing constant blinking symptom of TD. Woman experiencing finger tapping symptom of TD. Woman experiencing lip puckering symptom of TD. Man experiencing portraying tongue darting symptom of TD.

See the symptoms2,3

Don't let TD

Do you or a loved one have a TD diagnosis?

Don't let TD

Are you or your loved one taking

Impact of TD2-8,10

Having TD can be frustrating and overwhelming. In addition to the physical effects, TD may affect some people emotionally, too, by
causing embarrassment and social withdrawal.

Uncontrollable movements make it difficult to perform everyday tasks and activities and affect you in ways others may not see, such as
causing increased anxiety in social settings. This increased anxiety
may even make TD movements worse.

The unintentional and
uncontrollable movements
of TD can2,6,10:

  • Be mistaken for being drunk or on drugs
  • Make it difficult to speak clearly
  • Attract unwanted attention when you’re out in public
  • Affect your ability to read or write
  • Make cutting your food or holding your drink challenging

No clinical trials have been conducted to suggest treating TD affects these outcomes.

“I had these movements, and I became really self-conscious.
I like to control my environment, my body, but I had no self-control over those movements.”

Sherland, living with TD.

Individual results may vary.

See how Sherland took charge
of her involuntary movements

Hear from real people with TD

Some people with TD recall not noticing their
movements until
family members
pointed them out.2,3,11

See their stories

Get the conversation going

Whether you're ready to talk to your healthcare provider about
involuntary movements or still
trying to figure out what to say, we have
an Appointment Preparation Guide to help you
start the conversation.

Start your guide

Approved Uses

AUSTEDO® XR (deutetrabenazine) extended-release tablets and AUSTEDO® (deutetrabenazine) tablets are prescription medicines that are used to treat:

  • the involuntary movements (chorea) of Huntington’s disease. AUSTEDO XR and AUSTEDO do not cure the cause of the involuntary movements, and it does not treat other symptoms of Huntington’s disease, such as problems with thinking or emotions.
  • movements in the face, tongue, or other body parts that cannot be controlled (tardive dyskinesia).

It is not known if AUSTEDO XR and AUSTEDO are safe and effective in children.

Important Safety Information

AUSTEDO XR and AUSTEDO can cause serious side effects in people with Huntington’s disease, including: depression, suicidal thoughts, or suicidal actions. Do not start taking AUSTEDO XR or AUSTEDO if you are depressed (have untreated depression or depression that is not well controlled by medicine) or have suicidal thoughts. Pay close attention to any changes, especially sudden changes, in mood, behaviors, thoughts or feelings. This is especially important when AUSTEDO XR or AUSTEDO is started and when the dose is changed. Call your healthcare provider right away if you become depressed, have unusual changes in mood or behavior, or have thoughts of suicide.

Do not take AUSTEDO XR or AUSTEDO if you:

  • have Huntington’s disease and are depressed or have thoughts of suicide.
  • have liver problems.
  • are taking reserpine. Do not take medicines that contain reserpine with AUSTEDO XR or AUSTEDO. If your healthcare provider plans to switch you from taking reserpine to AUSTEDO XR or AUSTEDO, you must wait at least 20 days after your last dose of reserpine before you start taking AUSTEDO XR or AUSTEDO.
  • are taking a monoamine oxidase inhibitor (MAOI) medicine. Do not take an MAOI within 14 days after you stop taking AUSTEDO XR or AUSTEDO. Do not start AUSTEDO XR or AUSTEDO if you stopped taking an MAOI in the last 14 days. Ask your healthcare provider or pharmacist if you are not sure.
  • are taking tetrabenazine. If your healthcare provider plans to switch you from tetrabenazine to AUSTEDO XR or AUSTEDO, take your first dose of AUSTEDO XR or AUSTEDO on the day after your last dose of tetrabenazine.
  • are taking valbenazine.

Other possible serious side effects include:

  • Irregular heartbeat (QT prolongation). AUSTEDO XR and AUSTEDO increases your chance of having certain changes in the electrical activity in your heart. These changes can lead to a dangerous abnormal heartbeat. Taking AUSTEDO XR or AUSTEDO with certain medicines may increase this chance.
  • Neuroleptic Malignant Syndrome. Call your healthcare provider right away and go to the nearest emergency room if you develop these signs and symptoms that do not have another obvious cause: high fever, stiff muscles, problems thinking, very fast or uneven heartbeat, or increased sweating.
  • Restlessness. You may get a condition where you feel a strong urge to move. This is called akathisia.
  • Parkinsonism. Symptoms include: slight shaking, body stiffness, trouble moving, trouble keeping your balance, or falls.

Sleepiness (sedation) is a common side effect of AUSTEDO XR and AUSTEDO. While taking AUSTEDO XR or AUSTEDO, do not drive a car or operate dangerous machinery until you know how AUSTEDO XR or AUSTEDO affects you. Drinking alcohol and taking other drugs that may also cause sleepiness while you are taking AUSTEDO XR or AUSTEDO may increase any sleepiness caused by AUSTEDO XR and AUSTEDO.

The most common side effects of AUSTEDO in people with Huntington’s disease include sleepiness (sedation), diarrhea, tiredness, and dry mouth.

The most common side effects of AUSTEDO in people with tardive dyskinesia include inflammation of the nose and throat (nasopharyngitis) and problems sleeping (insomnia).

The most common side effects of AUSTEDO XR are expected to be similar to AUSTEDO in people with Huntington’s disease or tardive dyskinesia.

These are not all the possible side effects of AUSTEDO XR or AUSTEDO. Call your doctor for medical advice about side effects. You are encouraged to report side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch or call 1-800-FDA-1088.

Please read the accompanying Medication Guide.

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1. AUSTEDO® XR (deutetrabenazine) extended-release tablets/AUSTEDO® tablets current Prescribing Information. Parsippany, NJ: Teva Neuroscience, Inc.

2. Warikoo N, Schwartz TL, Citrome L. Tardive dyskinesia. In: Schwartz TL, Megna J, Topel ME, eds. Antipsychotic Drugs. Nova Science Publishers, Inc.; 2013:235-258.

3. Waln O, Jankovic J. An update on tardive dyskinesia: from phenomenology to treatment. Tremor Other Hyperkinet Mov (N Y). 2013;3:tre-03-161-4138-1. doi:10.7916/D88P5Z71

4. About mental health. Centers for Disease Control and Prevention. Accessed February 27, 2023. https://www.cdc.gov/mentalhealth/learn/

5. Jain R, Correll CU. Tardive dyskinesia: recognition, patient assessment, and differential diagnosis. J Clin Psychiatry. 2018;79(2):nu17034ah1c. doi:10.4088/JCP.nu17034ah1c

6. Jackson R, Brams MN, Citrome L, et al. Assessment of the impact of tardive dyskinesia in clinical practice: consensus panel recommendations. Neuropsychiatr Dis Treat. 2021;17:1589-1597. doi:10.2147/NDT.S310605

7. Tardive dyskinesia. National Alliance on Mental Illness. Accessed February 16, 2023. https://www.nami.org/About-Mental-Illness/Treatments/Mental-Health-Medications/Tardive-Dyskinesia

8. Bergland C. Is tardive dyskinesia reversible? Verywell Health. March 8, 2022. Accessed January 9, 2023. https://www.verywellhealth.com/is-tardive-dyskinesia-reversible-5217232#

9. Data on file. Parsippany, NJ: Teva Neuroscience, Inc.

10. Derrow P. What is tardive dyskinesia? Symptoms, causes, diagnosis, treatment, and prevention. Everyday Health. Accessed February 28, 2023. https://www.everydayhealth.com/tardive-dyskinesia/

11. My loved one has started moving strangely. Mental Health America. Accessed January 8, 2024. https://screening.mhanational.org/content/my-loved-one-has-started-moving-strangely/